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Karen Yee Selected Research

RO6839921

10/2020Phase 1 study of the MDM2 antagonist RO6839921 in patients with acute myeloid leukemia.

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Karen Yee Research Topics

Disease

13Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2022 - 01/2008
9Neoplasms (Cancer)
06/2019 - 04/2008
7Myelodysplastic Syndromes (Myelodysplastic Syndrome)
05/2022 - 04/2011
7Leukemia
02/2016 - 11/2005
5Hematologic Neoplasms (Hematological Malignancy)
01/2017 - 12/2008
2Kidney Diseases (Kidney Disease)
01/2021 - 01/2021
2Primary Myelofibrosis (Myelosclerosis)
09/2017 - 11/2015
1Nausea
03/2022
1Tumor Lysis Syndrome
03/2022
1Venous Thromboembolism
12/2020
1Pulmonary Embolism
12/2020
1Venous Thrombosis (Deep-Vein Thrombosis)
12/2020
1Thrombosis (Thrombus)
12/2020
1Opioid-Related Disorders (Opiate Addiction)
11/2020
1Chronic Myelomonocytic Leukemia (Leukemia, Chronic Myelomonocytic)
01/2020
1Chromosome Aberrations (Chromosome Abnormalities)
10/2018
1Nephrotic Syndrome (Syndrome, Nephrotic)
07/2018
1Fatigue
04/2016
1Insulin Resistance
12/2014
1Cardiovascular Diseases (Cardiovascular Disease)
12/2014
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
02/2013
1Philadelphia Chromosome
02/2013
1Multiple Myeloma
05/2012
1Second Primary Neoplasms (Neoplasms, Second)
04/2008

Drug/Important Bio-Agent (IBA)

6Cytarabine (Cytosar-U)FDA LinkGeneric
10/2021 - 11/2005
3Pharmaceutical PreparationsIBA
03/2022 - 09/2015
3Glutens (Glutelin)IBA
01/2021 - 07/2018
2BilirubinIBA
03/2022 - 04/2016
2Mitoxantrone (Novantrone)FDA LinkGeneric
10/2021 - 01/2008
2Proteins (Proteins, Gene)FDA Link
01/2021 - 12/2008
2RG7388IBA
01/2021 - 01/2016
2guadecitabineIBA
06/2019 - 09/2015
1Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
05/2022
1Hypoglycemic Agents (Hypoglycemics)IBA
05/2022
1Alanine Transaminase (SGPT)IBA
03/2022
1Aspartate Aminotransferases (Aspartate Transaminase)IBA
03/2022
1GSK2879552IBA
01/2022
1Lysine (L-Lysine)FDA Link
01/2022
1alvocidib (flavopiridol)IBA
10/2021
1Biomarkers (Surrogate Marker)IBA
10/2021
1C-Type Lectins (C-Type Lectin)IBA
01/2021
1DCLL9718SIBA
01/2021
1Core Binding Factors (Core-Binding Factor)IBA
01/2021
1Immunoconjugates (Immunoconjugate)IBA
01/2021
1Asparaginase (Elspar)FDA Link
12/2020
1Naloxone Drug Combination BuprenorphineFDA Link
11/2020
1RO6839921IBA
10/2020
1cedazuridineIBA
01/2020
1DecitabineFDA Link
01/2020
1AlbuminsIBA
10/2018
1Gonadotropin-Releasing Hormone (GnRH)FDA Link
01/2018
1Hormones (Hormone)IBA
01/2018
1Exportin 1 ProteinIBA
01/2017
1Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA
01/2017
1selinexorIBA
01/2017
1OTX015IBA
04/2016
1RG7112IBA
02/2016
1Proto-Oncogene Proteins c-mdm2IBA
01/2016
1acivicin (AT 125)IBA
09/2015
1Glucose (Dextrose)FDA LinkGeneric
12/2014
1HDL LipoproteinsIBA
12/2014
1LDL Lipoproteins (beta Lipoproteins)IBA
12/2014
1LDL CholesterolIBA
12/2014
1Insulin (Novolin)FDA Link
12/2014
1CarbohydratesIBA
12/2014
1LipidsIBA
12/2014
1Triglycerides (Triacylglycerol)IBA
12/2014
1HDL CholesterolIBA
12/2014
1Dietary Carbohydrates (Carbohydrate, Dietary)IBA
12/2014
1tosedostatIBA
04/2013
1Vincristine (Oncovin)FDA LinkGeneric
02/2013
1Liposomes (Liposome)IBA
02/2013
1IonophoresIBA
10/2012
1Clioquinol (Vioform)FDA Link
10/2012
1MetalsIBA
10/2012
1Biological ProductsIBA
10/2012
1Proteasome Endopeptidase Complex (Proteasome)IBA
10/2012
1linifanibIBA
08/2012
1ENMD 2076IBA
05/2012
1Aurora Kinase AIBA
05/2012
1Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA
05/2012
1Aurora KinasesIBA
05/2012
1Phosphotransferases (Kinase)IBA
05/2012
1Azacitidine (5 Azacytidine)FDA Link
04/2011
1Tyrosine (L-Tyrosine)FDA Link
03/2011
1lestaurtinibIBA
03/2011
1obatoclaxIBA
12/2008
1Daunorubicin (Cerubidine)FDA LinkGeneric
01/2008

Therapy/Procedure

11Therapeutics
01/2022 - 01/2008
6Drug Therapy (Chemotherapy)
12/2020 - 01/2008
1Hematopoietic Stem Cell Transplantation
01/2021
1Catheters
12/2020
1Erythrocyte Transfusion
11/2015
1Carbohydrate-Restricted Diet (Low Carbohydrate Diet)
12/2014
1Cell Transplantation
02/2013
1Intravenous Infusions
12/2008
1Radiotherapy
04/2008
1Aftercare (After-Treatment)
04/2008
1Complementary Therapies (Alternative Medicine)
02/2008
1Induction Chemotherapy
01/2008